IGF-1 LR3

Description

IGF-1 LR3 (Long R3 IGF-1) is a modified analog of insulin-like growth factor-1 featuring an N-terminal extension and an arginine substitution that reduce binding-protein interference in culture. It is widely referenced in in vitro laboratory research examining IGF-1 receptor binding, cell proliferation assays, and growth-factor signaling pathways.

Plumeo Research supplies IGF-1 LR3 in lyophilized form at ≥99% purity, verified by HPLC and mass spectrometry, with a Certificate of Analysis available for every batch.

Intended exclusively for in vitro laboratory research by qualified investigators. Not for human, veterinary, or clinical use.

Areas of Research Interest

• IGF-1 receptor binding assays
• Cell proliferation and viability assays in culture
• Growth-factor signaling pathway research
• PI3K/Akt and MAPK in vitro signaling studies
• Recombinant growth-factor reference applications

Technical Properties

• Class: IGF-1 analog (83 aa)
• Molecular Weight: ≈ 9117.6 g/mol
• CAS Number: 946870-92-4
• Purity: ≥99% (HPLC verified)
• Appearance: White lyophilized powder
• Solubility: Soluble in dilute acetic acid / bacteriostatic water

Storage & Handling

• Store lyophilized product at -20°C, protected from light and moisture.
• Once reconstituted, store at 2–8°C and use within the recommended stability window.
• Avoid repeated freeze-thaw cycles to preserve peptide integrity.
• Handle in accordance with standard laboratory safety practices (PPE, sterile technique).
• Verify molecular data against the supplied Certificate of Analysis (COA) before use.

FOR LABORATORY AND RESEARCH USE ONLY. Not for human consumption, therapeutic use, veterinary use, or in vivo diagnostic procedures. Not a drug, food, or cosmetic. Products are sold exclusively to qualified researchers and laboratory professionals for in vitro investigational purposes. By purchasing, the buyer affirms they are a licensed researcher and assume full responsibility for proper handling, use, and disposal in compliance with all applicable laws.